Foscarnet dosages must be adjusted according to renal function. Low white blood cell counts have happened with foscarnet. Individually dispensed doses of foscarnet should be aseptically transferred and diluted with equal parts of 0. Foscarnet injection comes as a liquid to be intravenously into a vein. Foscarnet sodico dosificacion, efectos secundarios infosida. Foscarnet sodico appare come una polvere cristallina biancastra contenente 6 equivalenti di acqua di idratazione e formula molecolare na3co5p 6 h2o di peso molecolare pari a a 300,1 grammi mole.
Foscarnet should be administered by the intravenous route only, either by a central venous line or in a peripheral vein. Foscarnet update december 2017 the society of hospital. A type of abnormal heartbeat prolonged qt interval has happened with foscarnet. Foscarnet has in vitro activity against human herpesvirus 6a and 6b, and has been used in a few cases.
Infusions of foscarnet 120 to 200 mgkgday for up to 4 weeks are given for aciclovirresistant herpes virus infections. It is usually infused slowly over 1 to 2 hours every 8 or 12 hours. When peripheral veins are used, the solution of foscarnet 24 mgml must be diluted. Jan 26, 2020 a type of abnormal heartbeat prolonged qt interval has happened with foscarnet. You may receive foscarnet injection in a hospital or you may administer the medication at home. Australian injectable drugs handbook 7th edition update december 2017 229 foscarnet synonyms foscarnet sodium brand name foscavir drug class antiviral availability glass bottle contains 6g250ml of foscarnet sodium hexahydrate.
It is classified as a pyrophosphate analog dna polymerase inhibitor. If your institution subscribes to this resource, and you dont have a myaccess profile, please contact your librarys reference desk for information on how to gain access to this resource from offcampus. Intravitreal administration to patients with cmv retinitis has been reported. Foscarnet is the conjugate base of a chemical compound with the formula ho 2 cpo 3 h 2. Call your doctor right away if you have a fast or abnormal heartbeat, or if you pass out. Inyectar foscarnet demasiado rapido puede causar efectos secundarios peligrosos o no deseados. Foscarnet must be given intravenously, and side effects including nausea, fever, headache, anemia, and renal failure are common. Composicion, indicaciones, presentacion y contraindicaciones. Clinically, foscarnet is employed almost exclusively to treat infections with cytomegalovirus cmv particularly when ganciclovir cannot be used and acyclovirresistant herpes simplex virus hsv and varicella zoster virus vzv. Foscarnet phosphonomethanoic acid is an antiviral medication which is primarily used to treat viral infections involving the herpesviridae family. It is recommended that the solution be used within 24 hours of dilution.
Over 10 million scientific documents at your fingertips. Antivirales universidad centroccidental lisandro alvarado. The length of your treatment depends on how you respond to the medication. You may receive foscarnet injection in a hospital or.